A very high percentage of drug candidates in development are insoluble. These compounds often have low bioavailability due to solubility or dissolution limited absorption. Unconventional formulations based on amorphous solid can often provide improved exposure over conventional formulations based on crystalline material, and have become a very attractive formulation platform. Our amorphous solid dispersion screening is designed to evaluate the feasibility and risk of using an amorphous formulation and help clients make informed decisions on formulation development.