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Drug-Excipient Compatibility Screening


All formulations contain excipients making the interaction between API and excipients crucial in many aspects. For example, an excipient may affect the degradation rate and/or mechanism of the API.  Additionally, excipients can significantly alter API dissolution.  Excipients can also cause the API to change its solid state nature by forming a co-crystal or causing an API salt to disproportionate. Our Drug-Excipient Compatibility Screening will help select optimal excipients for formulation and avoid the costly investment arising from excipient incompatibility.

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  HIGHLIGHTS  

  Salt/Polymorph/Co-crystal Screening
Chiral Resolution Screening
API Form Selection and Optimization
Solid State NMR Service

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