Solubility is a physical attribute that is required in many solvent systems for many applications during the lifetime of an API in drug development.  Obtaining accurate solubility measurements is non-trivial and requires significant attention to temperature control, KF of the solvent, handling of the supernatant, and scrutinizing the physical form of the remaining solids.  Crystal Pharmatech has more than 20 years combined experience in obtaining accurate solubility measurements for such applications including but not limited to: WMA filings, crystallization development, yield and productivity enhancement, and liquid-filled capsule excipient choice.